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Effects of acyl chain length, unsaturation, and pH on thermal stability of model discoidal HDLs

HDLs prevent atherosclerosis by removing excess cell cholesterol. Lipid composition affects HDL functions in cholesterol removal, yet its effects on the disk stability remain unclear. We hypothesize that reduced length or increased cis-unsaturation of phosphatidylcholine acyl chains destabilize disc...

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Bibliographic Details
Main Authors: Guha, Madhumita, Gantz, Donald L., Gursky, Olga
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2444001/
https://ncbi.nlm.nih.gov/pubmed/18456639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800106-JLR200
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