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Positional enhancer-blocking activity of the chicken β-globin insulator in transiently transfected cells

It is thought that insulators demarcate transcriptionally and structurally independent chromatin domains. Insulators are detected by their ability to block enhancer–promoter interactions in a directional manner, and protect a transgene from position effects. Most studies are performed in stably tran...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Recillas-Targa, Félix, Bell, Adam C., Felsenfeld, Gary
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24440/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10588709/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.25.14354
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