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Positional enhancer-blocking activity of the chicken β-globin insulator in transiently transfected cells

It is thought that insulators demarcate transcriptionally and structurally independent chromatin domains. Insulators are detected by their ability to block enhancer–promoter interactions in a directional manner, and protect a transgene from position effects. Most studies are performed in stably tran...

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Bibliographische Detailangaben
Hauptverfasser: Recillas-Targa, Félix, Bell, Adam C., Felsenfeld, Gary
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24440/
https://ncbi.nlm.nih.gov/pubmed/10588709
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