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L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice
We hypothesized that the apolipoprotein mimetic peptide L-4F, which induces arterial anti-oxidative enzymes and is vasoprotective in a rat model of diabetes, would ameliorate insulin resistance and diabetes in obese mice. L-4F (2 mg/kg/d) administered to ob/ob mice for 6 weeks limited weight gain wi...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2443999/ https://ncbi.nlm.nih.gov/pubmed/18426778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800046-JLR200 |
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