Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer

We determined the 2.45 Å crystal structure of the nucleosome core particle from Drosophila melanogaster and compared it to that of Xenopus laevis bound to the identical 147 base-pair DNA fragment derived from human α-satellite DNA. Differences between the two structures primarily reflect 16 amino ac...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Clapier, Cedric R, Chakravarthy, Srinivas, Petosa, Carlo, Fernández-Tornero, Carlos, Luger, Karolin, Müller, Christoph W
Materialtyp: Artigo
Språk:Inglês
Publicerad: Wiley Subscription Services, Inc., A Wiley Company 2008
Ämnen:
Short Communication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443955/
https://ncbi.nlm.nih.gov/pubmed/17957772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21720
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