Assessment of Aspergillus fumigatus Burden in Pulmonary Tissue of Guinea Pigs by Quantitative PCR, Galactomannan Enzyme Immunoassay, and Quantitative Culture

Early diagnosis of invasive pulmonary aspergillosis is problematic in some patient groups due to the lack of rapid, sensitive, specific, and reliable diagnostic tests. Fungal burden and therapeutic efficacy were assessed by survival, quantitative culture (CFU counts), galactomannan enzyme immunoassa...

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Main Authors: Vallor, Ana C., Kirkpatrick, William R., Najvar, Laura K., Bocanegra, Rosie, Kinney, Marsha C., Fothergill, Annette W., Herrera, Monica L., Wickes, Brian L., Graybill, John R., Patterson, Thomas F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443907/
https://ncbi.nlm.nih.gov/pubmed/18474582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00276-08
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