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Telavancin Penetration into Human Epithelial Lining Fluid Determined by Population Pharmacokinetic Modeling and Monte Carlo Simulation

Telavancin is an investigational bactericidal lipoglycopeptide with a multifunctional mechanism of action, as demonstrated against methicillin-resistant Staphylococcus aureus. While the plasma pharmacokinetics have been described, the extent of the penetration of the drug into the lung, measured by...

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Detalhes bibliográficos
Main Authors: Lodise, Thomas P., Gotfried, Mark, Barriere, Steven, Drusano, George L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443895/
https://ncbi.nlm.nih.gov/pubmed/18426898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01110-07
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