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Genotype-Specific Recurrence Risks as Indicators of the Genetic Architecture of Complex Diseases
A statistic is introduced that relates discoveries made in genome-wide association (GWA) studies to patterns of disease risks among relatives. The genotype-specific recurrence risk (GSR) is the genotype-specific risk to relatives of known relationship to affected probands. The GSRs can be used for t...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2008
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2443843/ https://ncbi.nlm.nih.gov/pubmed/18597734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.06.011 |
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