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Prostaglandin-mediated closure of paracellular pathway and not restitution is the primary determinant of barrier recovery in acutely injured porcine ileum

Small bowel epithelium is at the frontline of intestinal barrier function. Restitution is considered to be the major determinant of epithelial repair as function recovers in parallel with restitution after acute injury. As such, studies of intact mucosa have largely been replaced by migration assays...

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Autori principali: Gookin, Jody L., Galanko, Joseph A., Blikslager, Anthony T., Argenzio, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443786/
https://ncbi.nlm.nih.gov/pubmed/12801887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00532.2002
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