Larazotide acetate induces recovery of ischemia-injured porcine jejunum via repair of tight junctions

Intestinal ischemia results in mucosal injury, including paracellular barrier loss due to disruption of tight junctions. Larazotide acetate (LA), a small peptide studied in Phase III clinical trials for treatment of celiac disease, regulates tight junctions (TJs). We hypothesized that LA would dose-...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Slifer, Zachary M., Hernandez, Liliana, Pridgen, Tiffany A., Carlson, Alexandra R., Messenger, Kristen M., Madan, Jay, Krishnan, B. Radha, Laumas, Sandeep, Blikslager, Anthony T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8061941/
https://ncbi.nlm.nih.gov/pubmed/33886649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0250165
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi