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Correlation of the structural and functional domains in the membrane protein Vpu from HIV-1

Vpu is an 81-residue membrane protein encoded by the HIV-1 genome. NMR experiments show that the protein folds into two distinct domains, a transmembrane hydrophobic helix and a cytoplasmic domain with two in-plane amphipathic α-helices separated by a linker region. Resonances in one-dimensional sol...

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Bibliografiske detaljer
Main Authors: Marassi, F. M., Ma, C., Gratkowski, H., Straus, S. K., Strebel, K., Oblatt-Montal, M., Montal, M., Opella, S. J.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24437/
https://ncbi.nlm.nih.gov/pubmed/10588706
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