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Analysis of Substrate-Binding Elements in OxlT, the Oxalate:Formate Antiporter of Oxalobacter formigenes

An OxlT homology model suggests R272 and K355 in transmembrane helices 8 and 11, respectively, are critical to OxlT-mediated transport. We offer positive evidence supporting this idea by studying OxlT function after cysteine residues were separately introduced at these positions. Without further tre...

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Détails bibliographiques
Auteurs principaux: Wang, Xicheng, Sarker, Rafiquel I., Maloney, Peter C.
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443686/
https://ncbi.nlm.nih.gov/pubmed/16922510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060746v
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