Structural Determinants of Ca(2+) Permeability and Conduction in the Human 5-Hydroxytryptamine Type 3A Receptor

Cation-selective cysteine (Cys)-loop transmitter-gated ion channels provide an important pathway for Ca(2+) entry into neurones. We examined the influence on Ca(2+) permeation of amino acids located at intra- and extracellular ends of the conduction pathway of the human 5-hydroxytryptamine type 3A (...

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Hauptverfasser: Livesey, Matthew R., Cooper, Michelle A., Deeb, Tarek Z., Carland, Jane E., Kozuska, Janna, Hales, Tim. G., Lambert, Jeremy J., Peters, John A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Membrane Transport, Structure, Function, and Biogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443672/
https://ncbi.nlm.nih.gov/pubmed/18474595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802406200
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