Rapid, Opioid-sensitive Mechanisms Involved in Transient Receptor Potential Vanilloid 1 Sensitization

TRPV1 is a nociceptive, Ca(2+)-selective ion channel involved in the development of several painful conditions. Sensitization of TRPV1 responses by cAMP-dependent PKA crucially contributes to the development of inflammatory hyperalgesia. However, the pathways involved in potentiation of TRPV1 respon...

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Main Authors: Vetter, Irina, Cheng, Wei, Peiris, Madusha, Wyse, Bruce D., Roberts-Thomson, Sarah J., Zheng, Jie, Monteith, Gregory R., Cabot, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443658/
https://ncbi.nlm.nih.gov/pubmed/18482991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707865200
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