miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

BACKGROUND: Glioblastoma multiforme (GBM) is an invariably fatal central nervous system tumor despite treatment with surgery, radiation, and chemotherapy. Further insights into the molecular and cellular mechanisms that drive GBM formation are required to improve patient outcome. MicroRNAs are emerg...

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Bibliographic Details
Main Authors: Silber, Joachim, Lim, Daniel A, Petritsch, Claudia, Persson, Anders I, Maunakea, Alika K, Yu, Mamie, Vandenberg, Scott R, Ginzinger, David G, James, C David, Costello, Joseph F, Bergers, Gabriele, Weiss, William A, Alvarez-Buylla, Arturo, Hodgson, J Graeme
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443372/
https://ncbi.nlm.nih.gov/pubmed/18577219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-6-14
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