miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

BACKGROUND: Glioblastoma multiforme (GBM) is an invariably fatal central nervous system tumor despite treatment with surgery, radiation, and chemotherapy. Further insights into the molecular and cellular mechanisms that drive GBM formation are required to improve patient outcome. MicroRNAs are emerg...

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Main Authors: Silber, Joachim, Lim, Daniel A, Petritsch, Claudia, Persson, Anders I, Maunakea, Alika K, Yu, Mamie, Vandenberg, Scott R, Ginzinger, David G, James, C David, Costello, Joseph F, Bergers, Gabriele, Weiss, William A, Alvarez-Buylla, Arturo, Hodgson, J Graeme
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443372/
https://ncbi.nlm.nih.gov/pubmed/18577219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-6-14
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