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Can single knockouts accurately single out gene functions?

BACKGROUND: When analyzing complex biological systems, a major objective is localization of function – assessing how much each element contributes to the execution of specific tasks. To establish causal relationships, knockout and perturbation studies are commonly executed. The vast majority of stud...

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Detalhes bibliográficos
Main Authors: Deutscher, David, Meilijson, Isaac, Schuster, Stefan, Ruppin, Eytan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443110/
https://ncbi.nlm.nih.gov/pubmed/18564419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-2-50
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