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Network-Free Inference of Knockout Effects in Yeast

Perturbation experiments, in which a certain gene is knocked out and the expression levels of other genes are observed, constitute a fundamental step in uncovering the intricate wiring diagrams in the living cell and elucidating the causal roles of genes in signaling and regulation. Here we present...

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Autori principali: Peleg, Tal, Yosef, Nir, Ruppin, Eytan, Sharan, Roded
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795781/
https://ncbi.nlm.nih.gov/pubmed/20066032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000635
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