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Glyconanobiotics: Novel carbohydrated nanoparticle antibiotics for MRSA and Bacillus anthracis

This report describes the synthesis and evaluation of glycosylated polyacrylate nanoparticles that have covalently-bound antibiotics within their framework. The requisite glycosylated drug monomers were prepared from one of three known antibiotics, an N-sec-butylthio β-lactam, ciprofloxacin, and a p...

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Detalhes bibliográficos
Main Authors: Abeylath, Sampath C., Turos, Edward, Dickey, Sonja, Limb, Daniel V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442916/
https://ncbi.nlm.nih.gov/pubmed/18063370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.11.052
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