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Antibiotic-Conjugated Polyacrylate Nanoparticles: New Opportunities for Development of Anti-MRSA Agents

This report describes the preparation of polyacrylate nanoparticles in which an N-thiolated β-lactam antibiotic is covalently conjugated onto the polymer framework. These nanoparticles are formed in water by emulsion polymerization of an acrylated antibiotic pre-dissolved in a liquid acrylate monome...

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Detalhes bibliográficos
Main Authors: Turos, Edward, Shim, Jeung-Yeop, Wang, Yang, Greenhalgh, Kerriann, Reddy, G. Suresh Kumar, Dickey, Sonja, Lim, Daniel V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798659/
https://ncbi.nlm.nih.gov/pubmed/17049850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.09.098
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