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Diseases Caused by Defects in the Visual Cycle: Retinoids as Potential Therapeutic Agents
Absorption of a photon by an opsin pigment causes isomerization of the chromophore from 11-cis-retinaldehyde to all-trans-retinaldehyde. Regeneration of visual chromophore following light exposure is dependent on an enzyme pathway called the retinoid or visual cycle. Our understanding of this pathwa...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442882/ https://ncbi.nlm.nih.gov/pubmed/16968212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.pharmtox.47.120505.105225 |
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