Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3(+)CD4(+) regulatory T cells

Although mature dendritic cells (DCs) are potent initiators of adaptive immune response, immature steady-state DCs contribute to immune tolerance. In this study, we show that ex vivo splenic DCs are capable of inducing conversion of naïve CD4(+) T cells to adaptive Foxp3(+)CD4(+) regulatory T cells...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Li, Pino-Lagos, Karina, de Vries, Victor C., Guleria, Indira, Sayegh, Mohamed H., Noelle, Randolph J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442817/
https://ncbi.nlm.nih.gov/pubmed/18599457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710441105
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