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Tissue Specific Regulation of ACE/ACE2 and AT(1)/AT(2) Receptor Gene Expression By Estrogen in ApoE/ERα Knock-Out Mice

ACE and ACE2 and the AT(1) and AT(2) receptors are pivotal points of regulation in the renin-angiotensin system. ACE and ACE2 are key enzymes in the formation and degradation of Ang II and Ang-(1-7). Ang II acts at either the AT(1) or the AT(2) receptor to mediate opposing actions of vasoconstrictio...

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Detalhes bibliográficos
Main Authors: Brosnihan, K. Bridget, Hodgin, Jeffrey B., Smithies, Oliver, Maeda, Nobuyo, Gallagher, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442755/
https://ncbi.nlm.nih.gov/pubmed/18192335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2007.041806
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