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Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth

Canonical Wnt signaling is central to normal bone homeostasis, and secretion of Wnt signaling inhibitors by multiple myeloma (MM) cells contributes to MM-related bone resorption and disease progression. The aim of this study was to test the effect of Wnt3a on bone disease and growth of MM cells in v...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qiang, Ya-Wei, Shaughnessy, John D., Yaccoby, Shmuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442747/
https://ncbi.nlm.nih.gov/pubmed/18344425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-10-120253
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