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Decreased brain reward function during nicotine withdrawal in C57BL6 mice: Evidence from intracranial self-stimulation (ICSS) studies

Deficits in brain reward function during nicotine withdrawal may serve as an important substrate for negative reinforcement that contributes to the persistence of the tobacco habit in human smokers. The ability to assess withdrawal-associated reward deficits in genetically modified mice may facilita...

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Detalhes bibliográficos
Main Authors: Johnson, Paul M., Hollander, Jonathan A., Kenny, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442647/
https://ncbi.nlm.nih.gov/pubmed/18466962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.03.024
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