Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets

Interleukin-7 (IL-7) is a homeostatic cytokine for resting T cells with increasing serum and tissue levels during T cell depletion. In preclinical studies, IL-7 therapy exerts marked stimulating effects on T cell immune reconstitution in mice and primates. First-in-human clinical studies of recombin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Sportès, Claude, Hakim, Frances T., Memon, Sarfraz A., Zhang, Hua, Chua, Kevin S., Brown, Margaret R., Fleisher, Thomas A., Krumlauf, Michael C., Babb, Rebecca R., Chow, Catherine K., Fry, Terry J., Engels, Julie, Buffet, Renaud, Morre, Michel, Amato, Robert J., Venzon, David J., Korngold, Robert, Pecora, Andrew, Gress, Ronald E., Mackall, Crystal L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Rockefeller University Press 2008
विषय:
Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442646/
https://ncbi.nlm.nih.gov/pubmed/18573906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071681
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