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Effect of Lipid Peroxidation Products on the Activity of Human Retinol Dehydrogenase 12 (RDH12) and Retinoid Metabolism

Mutations in human Retinol Dehydrogenase 12 (RDH12) are known to cause photoreceptor cell death but the physiological function of RDH12 in photoreceptors remains poorly understood. In vitro, RDH12 recognizes both retinoids and medium-chain aldehydes as substrates. Our previous study suggested that R...

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Detalhes bibliográficos
Main Authors: Lee, Seung-Ah, Belyaeva, Olga V., Kedishvili, Natalia Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442580/
https://ncbi.nlm.nih.gov/pubmed/18396173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2008.03.004
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