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Hypothalamic Neural Projections are Permanently Disrupted in Diet-Induced Obese Rats

The arcuate nucleus of the hypothalamus (ARH) is a key component of hypothalamic pathways regulating energy balance and leptin is required for normal development of ARH projections. Diet-induced obesity (DIO) has a polygenic mode of inheritance and DIO individuals develop the metabolic syndrome when...

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Autori principali: Bouret, Sebastien G., Gorski, Judith N., Patterson, Christa M., Chen, Stephen, Levin, Barry E., Simerly, Richard B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442478/
https://ncbi.nlm.nih.gov/pubmed/18249177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2007.12.001
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