Persistent downregulation of hippocampal CREB mRNA parallels a Y-maze deficit in adolescent rats following semi-chronic amphetamine administration

BACKGROUND AND PURPOSE: We investigated possible differences in the impact of chronic amphetamine administration during adolescence and adulthood on aspects of behaviour and brain chemistry. EXPERIMENTAL APPROACH: Adult (n=32) and adolescent (n=32) male Sprague–Dawley rats were given either D-amphet...

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Detalhes bibliográficos
Main Authors: Featherby, T, van den Buuse, M, Lubman, D I, Lawrence, A J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Focused Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442450/
https://ncbi.nlm.nih.gov/pubmed/18475255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.126
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