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Neuroplasticity in the mesolimbic dopamine system and cocaine addiction

The main characteristics of cocaine addiction are compulsive drug use despite adverse consequences and high rates of relapse during periods of abstinence. A current popular hypothesis is that compulsive cocaine use and cocaine relapse is due to drug-induced neuroadaptations in reward-related learnin...

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Bibliographic Details
Main Authors: Thomas, M J, Kalivas, P W, Shaham, Y
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442442/
https://ncbi.nlm.nih.gov/pubmed/18345022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.77
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