Plasmodium Food Vacuole Plasmepsins Are Activated by Falcipains

Intraerythrocytic malaria parasites use host hemoglobin as a major nutrient source. Aspartic proteases (plasmepsins) and cysteine proteases (falcipains) function in the early steps of the hemoglobin degradation pathway. There is extensive functional redundancy within and between these protease famil...

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Detalhes bibliográficos
Main Authors: Drew, Mark E., Banerjee, Ritu, Uffman, Eric W., Gilbertson, Scott, Rosenthal, Philip J., Goldberg, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442342/
https://ncbi.nlm.nih.gov/pubmed/18308731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708949200
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