Plasmodium Food Vacuole Plasmepsins Are Activated by Falcipains

Intraerythrocytic malaria parasites use host hemoglobin as a major nutrient source. Aspartic proteases (plasmepsins) and cysteine proteases (falcipains) function in the early steps of the hemoglobin degradation pathway. There is extensive functional redundancy within and between these protease famil...

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Bibliographische Detailangaben
Hauptverfasser: Drew, Mark E., Banerjee, Ritu, Uffman, Eric W., Gilbertson, Scott, Rosenthal, Philip J., Goldberg, Daniel E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442342/
https://ncbi.nlm.nih.gov/pubmed/18308731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708949200
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