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Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine

Hemoglobin degradation is a metabolic process that is central to the growth and maturation of the malaria parasite Plasmodium falciparum. Two aspartic proteases that initiate degradation, plasmepsins (PMs) I and II, have been identified and extensively characterized. Eight additional PM genes are pr...

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Detalhes bibliográficos
Main Authors: Banerjee, Ritu, Liu, Jun, Beatty, Wandy, Pelosof, Lorraine, Klemba, Michael, Goldberg, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC117418/
https://ncbi.nlm.nih.gov/pubmed/11782538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022630099
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