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A Close Association of RyRs with Highly Dense Clusters of Ca(2+)-activated Cl(−) Channels Underlies the Activation of STICs by Ca(2+) Sparks in Mouse Airway Smooth Muscle
Ca(2+) sparks are highly localized, transient releases of Ca(2+) from sarcoplasmic reticulum through ryanodine receptors (RyRs). In smooth muscle, Ca(2+) sparks trigger spontaneous transient outward currents (STOCs) by opening nearby clusters of large-conductance Ca(2+)-activated K(+) channels, and...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Rockefeller University Press
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442178/ https://ncbi.nlm.nih.gov/pubmed/18591421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709933 |
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