Dynamics of Signaling between Ca(2+) Sparks and Ca(2+)- Activated K(+) Channels Studied with a Novel Image-Based Method for Direct Intracellular Measurement of Ryanodine Receptor Ca(2+) Current

Ca(2+) sparks are highly localized cytosolic Ca(2+) transients caused by a release of Ca(2+) from the sarcoplasmic reticulum via ryanodine receptors (RyRs); they are the elementary events underlying global changes in Ca(2+) in skeletal and cardiac muscle. In smooth muscle and some neurons, Ca(2+) sp...

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Main Authors: ZhuGe, Ronghua, Fogarty, Kevin E., Tuft, Richard A., Lifshitz, Lawrence M., Sayar, Kemal, Walsh, John V.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2000
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231814/
https://ncbi.nlm.nih.gov/pubmed/11099351
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