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Spatiotemporal activation of Rac1 for engulfment of apoptotic cells

The engulfment of apoptotic cells requires phagocytes to coordinately activate Rho family GTPases that regulate actin dynamics. Here, we used a FRET biosensor to visualize the spatiotemporal activation of Rac1 during engulfment of apoptotic cells. We report that apoptotic cells were usually engulfed...

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Autors principals: Nakaya, Michio, Kitano, Masahiro, Matsuda, Michiyuki, Nagata, Shigekazu
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442128/
https://ncbi.nlm.nih.gov/pubmed/18591655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803677105
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