Comparison of p53 and the PDZ domain containing protein MAGI-3 regulation by the E6 protein from high-risk human papillomaviruses

Central to cellular transformation caused by human papillomaviruses (HPVs) is the ability of E6 proteins to target cellular p53 and proteins containing PDZ domains, including MAGI-3, for degradation. The aim of this study was to compare E6-mediated degradation of p53 and MAGI-3 under parallel experi...

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Detalhes bibliográficos
Main Authors: Ainsworth, Julia, Thomas, Miranda, Banks, Lawrence, Coutlee, Francois, Matlashewski, Greg
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442060/
https://ncbi.nlm.nih.gov/pubmed/18518978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-67
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