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RNA structure-based ribosome recruitment: Lessons from the Dicistroviridae intergenic region IRESes

In eukaryotes, the canonical process of initiating protein synthesis on an mRNA depends on many large protein factors and the modified nucleotide cap on the 5′ end of the mRNA. However, certain RNA sequences can bypass the need for these proteins and cap, using an RNA structure-based mechanism calle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pfingsten, Jennifer S., Kieft, Jeffrey S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441983/
https://ncbi.nlm.nih.gov/pubmed/18515544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.987808
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