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Human African trypanosomiasis: pharmacological re-engagement with a neglected disease

This review discusses the challenges of chemotherapy for human African trypanosomiasis (HAT). The few drugs registered for use against the disease are unsatisfactory for a number of reasons. HAT has two stages. In stage 1 the parasites proliferate in the haemolymphatic system. In stage 2 they invade...

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Detalhes bibliográficos
Main Authors: Barrett, M P, Boykin, D W, Brun, R, Tidwell, R R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441931/
https://ncbi.nlm.nih.gov/pubmed/17618313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707354
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