Llwytho...

The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone

Thyroid hormonogenesis requires secretion of thyroglobulin, a protein comprising Cys-rich regions I, II, and III (referred to collectively as region I-II-III) followed by a cholinesterase-like (ChEL) domain. Secretion of mature thyroglobulin requires extensive folding and glycosylation in the ER. Mu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lee, Jaemin, Di Jeso, Bruno, Arvan, Peter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441857/
https://ncbi.nlm.nih.gov/pubmed/18596923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35164
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