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Differential efficacy of combined therapy with radiation and AEE788 in a high and low EGFR expressing androgen independent prostate tumor models

PURPOSE: To determine the efficacy of combining radiation (XRT) with a dual EGFR/VEGFR inhibitor, AEE788, in prostate cancer models with different levels of EGFR expression. METHODS AND MATERIALS: Immunoblotting was performed for EGFR, phosphorylated-EGFR (p-EGFR), and p-AKT in prostate cancer cells...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Huamani, Jessica, Willey, Christopher, Thotala, Dinesh, Niermann, Kenneth J., Reyzer, Michelle, Leavitt, Lauren, Jones, Cameron, Fleishcher, Arthur, Caprioli, Richard, Hallahan, Dennis E., Kim, Dong Wook Nathan
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2008
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441843/
https://ncbi.nlm.nih.gov/pubmed/18337021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2007.12.049
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