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Electrochemical detection of low-copy number salivary RNA based on specific signal amplification with a hairpin probe

We developed a technique for electrochemical detection of salivary mRNA employing a hairpin probe (HP). Steric hindrance (SH) suppresses unspecific signal and generates a signal-on amplification process for target detection. The stem-loop configuration brings the reporter end of the probe into close...

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Detalhes bibliográficos
Main Authors: Wei, Fang, Wang, Jianghua, Liao, Wei, Zimmermann, Bernhard G., Wong, David T., Ho, Chih-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441804/
https://ncbi.nlm.nih.gov/pubmed/18487624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn299
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