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A hippocampal Cdk5 pathway regulates extinction of contextual fear

Treatment of emotional disorders involves the promotion of extinction processes, which are defined as the learned reduction of fear. The molecular mechanisms underlying extinction have only begun to be elucidated. By employing genetic and pharmacological approaches in mice, we show here that extinct...

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Main Authors: Sananbenesi, Farahnaz, Fischer, Andre, Wang, Xinyu, Schrick, Christina, Neve, Rachael, Radulovic, Jelena, Tsai, Li-Huei
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441763/
https://ncbi.nlm.nih.gov/pubmed/17632506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1943
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