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A hippocampal Cdk5 pathway regulates extinction of contextual fear

Treatment of emotional disorders involves the promotion of extinction processes, which are defined as the learned reduction of fear. The molecular mechanisms underlying extinction have only begun to be elucidated. By employing genetic and pharmacological approaches in mice, we show here that extinct...

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Bibliografische gegevens
Hoofdauteurs: Sananbenesi, Farahnaz, Fischer, Andre, Wang, Xinyu, Schrick, Christina, Neve, Rachael, Radulovic, Jelena, Tsai, Li-Huei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441763/
https://ncbi.nlm.nih.gov/pubmed/17632506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1943
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