Molecular and Genetic Analysis of Condensin Function in Vertebrate Cells

We engineered mutants into residues of SMC2 to dissect the role of ATPase function in the condensin complex. These residues are predicted to be involved in ATP binding or hydrolysis and in the Q-loop, which is thought to act as a mediator of conformational changes induced by substrate binding. All t...

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Main Authors: Hudson, Damien F., Ohta, Shinya, Freisinger, Tina, MacIsaac, Fiona, Sennels, Lau, Alves, Flavia, Lai, Fan, Kerr, Alastair, Rappsilber, Juri, Earnshaw, William C.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441691/
https://ncbi.nlm.nih.gov/pubmed/18480406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-01-0057
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