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EGF Transregulates Opioid Receptors through EGFR-mediated GRK2 Phosphorylation and Activation
G protein–coupled receptor (GPCR) kinases (GRKs) are key regulators of GPCR function. Here we demonstrate that activation of epidermal growth factor receptor (EGFR), a member of receptor tyrosine kinase family, stimulates GRK2 activity and transregulates the function of G protein–coupled opioid rece...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2441682/ https://ncbi.nlm.nih.gov/pubmed/18463167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-10-1058 |
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