Plasma Membrane Cholesterol Content Affects Nitric Oxide Diffusion Dynamics and Signaling

Nitric oxide (NO) signaling is inextricably linked to both its physical and chemical properties. Due to its preferentially hydrophobic solubility, NO molecules tend to partition from the aqueous milieu into biological membranes. We hypothesized that plasma membrane ordering provided by cholesterol f...

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Bibliographic Details
Main Authors: Miersch, Shane, Espey, Michael Graham, Chaube, Ruchi, Akarca, Arzu, Tweten, Rodney, Ananvoranich, Sirinart, Mutus, Bulent
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441544/
https://ncbi.nlm.nih.gov/pubmed/18445594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800440200
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