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LIPID PEROXIDATION-DERIVED ALDEHYDE-PROTEIN ADDUCTS CONTRIBUTE TO TRICHLOROETHENE-MEDIATED AUTOIMMUNITY VIA ACTIVATION OF CD4(+) T CELLS
Lipid peroxidation is implicated in the pathogenesis of various autoimmune diseases. Lipid peroxidation-derived aldehydes (LPDAs) such as malondialdehyde (MDA) and 4-hydroxynonenal (HNE) are highly reactive and bind to proteins, but their role in eliciting an autoimmune response and contribution to...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2440665/ https://ncbi.nlm.nih.gov/pubmed/18267128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.01.012 |
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