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Differential Regulation of the Cellular Response to DNA Double-strand Breaks in G1
Double-strand breaks (DSBs) are potentially lethal DNA lesions that can be repaired by either homologous recombination (HR) or non-homologous end-joining (NHEJ). We show that DSBs induced by ionizing radiation (IR) are efficiently processed for HR and bound by Rfa1 during G1, while endonuclease-indu...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2440653/ https://ncbi.nlm.nih.gov/pubmed/18406328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.01.016 |
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