Carbonic anhydrase related protein 8 mutation results in aberrant synaptic morphology and excitatory synaptic function in the cerebellum

Carbonic anhydrase related protein 8 (Car8) is known to be abundantly expressed in Purkinje cells (PCs), and its genetic mutation causes a motor coordination defect. To determine the underlying mechanism, we analyzed the mouse cerebellum carrying a Car8 mutation. Electrophysiological analysis showed...

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Hauptverfasser: Hirasawa, Michiru, Xu, Xinjie, Trask, Robert B., Maddatu, Terry P., Johnson, Britt A, Naggert, Jürgen K., Nishina, Patsy M., Ikeda, Akihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440645/
https://ncbi.nlm.nih.gov/pubmed/17376701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2007.02.013
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