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Cavity-Creating Mutations in Pseudomonas aeruginosa Azurin: Effects on Protein Dynamics and Stability

Changes in flexibility and structural stability of Pseudomonas aeruginosa azurin in response to cavity-creating mutations were probed by the phosphorescence emission of Trp-48, which was deeply buried in the compact hydrophobic core of the macromolecule, and by measurements of guanidinum hydrochlori...

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Detalhes bibliográficos
Main Authors: Gabellieri, Edi, Balestreri, Ettore, Galli, Alvaro, Cioni, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440464/
https://ncbi.nlm.nih.gov/pubmed/18424505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.128009
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